Research Article
Premature Valvular Heart Disease in Homozygous Familial Hypercholesterolemia
Table 2
FH patients with and without valvulopathy.
| | Characteristics | Valvulopathy () | No valvulopathy () | value |
| | Age, mean (SD) | 31 (14.41) | 17.5 (16.66) | 0.020 | | Female, % (N) | 52.38 (11) | 50 (6) | 1 | | LDL (mg/dL), mean (SD) | 436.7 (154.85) | 466.25 (149.21) | 0.50 | | HDL (mg/dL), mean (SD) | 39.46 (18.14) | 55.89 (36.29) | 0.13 | | Genetically homozygous, % (N) | 85 (18) | 75 (9) | 0.64 | | Apheresis, % (N) | 85.7 (18) | 50 (6) | 0.044 | | Apheresis years, mean (SD) | 7.33 (4.46) | 3.92 (5.32) | 0.072 | | IMT, mean (SD) | 0.62 (0.31) | 1.01 (0.64) | 0.035 | | Reduced ABI, % (N) | 28.57 (6) | 16.67 (2) | 0.68 | | Clinical CVD, % (N) | 38.10 (8) | 33.33 (4) | 1 |
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