Cholesterol Levels in Genetically Determined Familial Hypercholesterolaemia in Russian Karelia

Table 5

Comparison of patients with definite familial hypercholesterolaemia with and without LDL receptor gene mutations.

	LDL receptor gene mutations detected ()	LDL receptor gene mutations not detected ()	Statistical significance,
Males, (%)	8 (38.1)	40 (42.1)	0.112
Age, years	46 (28; 55)	53 (36; 63)	0.120
TC, mmol/L	10.3 (8.9; 11.0)	9.1 (8.0; 10.2)	0.013
LDL-C, mmol/L	7.6 (6.4; 8.4)	6,4 (5.4; 7.5)	0.006
HDL-C, mmol/L	1.5 (1.3; 1.7)	1.3 (1.1; 1.6)	0.117
TG, mmol/L	1.6 (1.3; 1.8)	1.7 (1.2; 2.2)	0.300

LDL-C: low density lipoprotein cholesterol.
FH: familial hypercholesterolaemia.
TC: total cholesterol.
HDL-C: high density lipoprotein cholesterol.
TG: triglycerides.
Results are presented as median and interquartile range, unless otherwise specified.