Modeling Spike-Train Processing in the Cerebellum Granular Layer and Changes in Plasticity Reveal Single Neuron Effects in Neural Ensembles

Table 5

Effect of inhibition on number of spikes in the detailed network model.

Number of inhibitory fiber synapses	In vitro				In vivo (short burst)				In vivo (long burst)
	4 MF	3 MF	2 MF	1 MF	4 MF	3 MF	2 MF	1 MF	4 MF	3 MF	2 MF	1 MF
0	2	1	0	0	7	5	3	0	8	6	3	0
1	2	1	0	0	6	4	2	0	7	5	2	0
2	1	1	0	0	5	3	0	0	6	4	1	0
3	1	1	0	0	4	2	0	0	5	3	0	0
4	1	1	0	0	3	1	0	0	4	2	0	0

The table shows the effect of inhibitory synapses on the spikes under different conditions (in vitro, in vivo (short burst); in vivo (long burst)). Under each condition, first row denotes increasing number (1–4) of excitatory synapses from right to left while increasing number of inhibitory synapses (0–4 in first column). With increase in number of inhibitory synapses (0–4), the number of spikes observed in the cells decreases. A gradual decrease in number of spikes with increased inhibition can be observed.