Research Article

Modelling Coupled Oscillations in the Notch, Wnt, and FGF Signaling Pathways during Somitogenesis: A Comprehensive Mathematical Model

Table 1

The sensitive parameters contained in the feedback loops.

Parameter perturbation Parameters associated with the feedback loop centred on Hes7Parameters associated with the feedback loop centred on LfngParameters associated with the feedback loop centred on Dusp4

+1%

+5%

+10%

−1%

−5%

−10%

The thin font represents that the periods of the target genes are positive correlation to the parameters; the thin italics represent that the periods of the target genes are negative correlation to the parameters; the bold font represent that the target genes do not oscillate under that perturbation level.