Altered Esophageal Mucosal Structure in Patients with Celiac Disease

Figure 1

(a) Examples of intracellular spaces in the esophageal mucosa of controls (C), GERD patient, active CD patient before gluten free diet (CD), and CD patient after one year of gluten-free diet (CD post GFD) assessed by light microscopy (A) and electron microscopy (B). Black arrows indicate dilated intracellular spaces (DIS). (b) Group DIS scores assessed by light microscopy, electron microscopy, and mRNA expression for zonula occludens-1 (ZO-1).

(a)

(b)