Research Article

Evaluation of Adrenal Function in Nonhospitalized Patients with Cirrhosis

Table 1

Demographic data and clinical characteristics of all patients, patients with normal adrenal function (group 1) and adrenal insufficiency (group 2).

All patientsGroup 1
(Normal Adrenal Function)
Group 2
(Adrenal Insufficiency)
  values for differences between group 1 and 2

Age40.5 ± 12.440.53 ± 12.9740.38 ± 11.840.963
Male sex (%)74 (70.48%)60 (67.4%)14 (87.5%)0.141
MELD score18.19 ± 5.4617.88 ± 5.3819.94 ± 5.730.188
CTP score8.70 ± 1.678.61 ± 1.699.25 ± 1.530.193
Total bilirubin (mg/dl)3.49 ± 3.043.55 ± 3.223.15 ± 1.70.64
Albumin (mg/dl)3.4 ± 0.613.45 ± 0.593.13 ± 0.680.095
Creatinine (mg/dl)1.11 ± 0.651.1 ± 0.691.17 ± 0.250.099
INR1.97 ± 0.941.88 ± 0.812.52 ± 1.350.032
Sodium (mEq/L)137.06 ± 7.43137.88 ± 7.16132.5 ± 7.530.012
Hyponatremia (%)32 (30.5%)10 (62.5%)22 (27.8%)0.006
Potassium (mEq/L)4.2 ± 0.544.15 ± 0.514.5 ± 0.590.045
Encephalopathy (%)79 (75.2%)70 (78.7%)9 (56.3%)0.067
Ascites (%)34 (32.4%)32 (36%)2 (12.5%)0.065
History of GIB (%)55 (52.4%)45 (50.6%)10 (62.5%)0.379
History of SBP (%)46 (43.8%)41 (46.1%)5 (31.25%)0.271

Data are presented as mean ± standard deviation; MELD: model for end stage liver disease; CTP: Child-Turcotte-Pugh; INR: international normalized ratio; GIB: gastrointestinal bleeding; SBP: spontaneous bacterial peritonitis.