Prevalence and Anatomic Distribution of Serrated and Adenomatous Lesions in Patients with Inflammatory Bowel Disease
Table 1
Patient and premalignant lesion characteristics.
Ad/D
SSA/P
TSA
All lesions
value
Assessment by patient ( (% of patients with each lesion))
Number of patients (% of all patients with lesions of interest)
64 (77.1)
18 (21.7)
4 (4.8)
83
<0.001
Gender
0.193
M
36 (56.3)
7 (38.9)
1 (25.0)
42 (50.6)
F
28 (43.8)
11 (61.1)
3 (75.0)
41 (49.4)
Age (years, mean ± SD)
56.4 ± 14.3
55.3 ± 13.4
56.3 ± 19.1
56.0 ± 14.2
0.762
IBD type
1.000
UC
30 (46.9)
8 (44.4)
2 (50.0)
38 (45.8)
CD
30 (46.9)
9 (50.0)
2 (50.0)
40 (48.2)
Unclassified
4 (6.3)
1 (5.6)
0 (0.0)
5 (6.0)
Assessment by lesion ( (% of lesion type))
Number of lesions (% of all lesions of interest)
96 (76.8)
25 (20.0)
4 (3.2)
125
<0.001
Gender
0.046
M
56 (58.3)
9 (36.0)
1 (25.0)
66 (52.8)
F
40 (41.7)
16 (64.0)
3 (75.0)
59 (47.2)
Age (years, mean ± SD)
56.5 ± 13.8
55.3 ± 13.4
53.3 ± 20.0
56.2 ± 13.8
0.702
Size (cm, mean ± SD)
0.58 ± 0.39
0.61 ± 0.34
0.73 ± 0.25
0.59 ± 0.38
0.711
IBD type
0.696
UC
52 (54.2)
12 (48.0)
2 (50.0)
66 (52.8)
CD
40 (41.7)
11 (44.0)
2 (50.0)
53 (42.4)
Unclassified
4 (4.2)
2 (8.0)
0 (0.0)
6 (4.8)
Location
Cecum
9 (9.4)
7 (28.0)
1 (25.0)
17 (13.6)
Ascending colon
17 (17.7)
7 (28.0)
1 (25.0)
25 (20.0)
Hepatic flexure
3 (3.1)
1 (4.0)
0 (0.0)
4 (3.2)
Transverse colon
13 (13.5)
6 (24.0)
0 (0.0)
19 (15.2)
Splenic flexure
3 (3.1)
1 (4.0)
0 (0.0)
4 (3.2)
Descending colon
15 (15.6)
1 (4.0)
1 (25.0)
17 (13.6)
Rectosigmoid
36 (37.5)
2 (8.0)
1 (25.0)
39 (31.2)
Location
Right colon
42 (43.8)
21 (84.0)
2 (50.0)
65 (52.0)
Left colon
54 (56.3)
4 (16.0)
2 (50.0)
60 (48.0)
Comparison between Ad/Ds and SSA/Ps only. Some patients have more than one lesion type. If there are multiple fragments, it represents size of largest fragment. Ad/D, conventional adenomas/dysplasia; CD, Crohn’s disease; IBD, inflammatory bowel disease; SSA/P, sessile serrated adenoma or polyp; SD, standard deviation; TSA, traditional serrated adenoma; UC, ulcerative colitis.
