Research Article

Efficacy and Safety of Immunosuppressive Therapy for PBC–AIH Overlap Syndrome Accompanied by Decompensated Cirrhosis: A Real-World Study

Table 4

Response to treatment in AIH features after 3, 6, and 12 months of therapy.

VariablesOverall (n=28, %)UDCA-only group (n=14), %UDCA+IS group (n=14), %P value

3-month remission4(14.2%)0(0%)4(28.6%)0.098
6-month remission6(21.4%)1(7.1%)5(35.7%)0.165
12-month remission7(33.3%)#1(9.1%)##6(60.0%)0.024

Twenty-one patients were treated for more than 12 months in total.
#Eleven patients were treated for more than 12 months in the UDCA-only group.
##Ten patients were treated for more than 12 months in the UDCA+IS group.