Increased Duodenal Iron Absorption through Upregulation of Ferroportin 1 due to the Decrement in Serum Hepcidin in Patients with Chronic Hepatitis C

<div>FPN expression in Caco-2/TC7 cell monolayers. FPN mRNA expression levels in Caco-2/TC7 cell monolayers cultured with or without hepcidin were measured by Taqman real-time PCR (a). FPN mRNA levels in Caco-2/TC7 cell monolayers were downregulated dependent on hepcidin concentration (P &lt;0.0001; Jonckheere–Terpstra test). FPN protein expression was analyzed by western blot (b). FPN protein in Caco-2/TC7 cell monolayers was downregulated dependently on hepcidin concentration.</div>

Canadian Journal of Gastroenterology and Hepatology

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Figure 5

Figure 5: Increased Duodenal Iron Absorption through Upregulation of Ferroportin 1 due to the Decrement in Serum Hepcidin in Patients with Chronic Hepatitis C 

Figure 5 | Increased Duodenal Iron Absorption through Upregulation of Ferroportin 1 due to the Decrement in Serum Hepcidin in Patients with Chronic Hepatitis C 