Primary Prophylaxis to Prevent the Development of Hepatic Encephalopathy in Cirrhotic Patients with Acute Variceal Bleeding

Table 3

Factors related to the development of hepatic encephalopathy in patients with cirrhosis after an acute episode of variceal bleeding. Univariate analysis.

Characteristic	Without HE	With HE	OR (95 CI)	P
	(n = 59)	(n = 28)
Rebleeding, n ()	7 (11.9)	15 (53.6)	8.6 (2.9 - 25.3)	<0.0001
Decompensated cirrhosis CHILD B/C, n ()	35 (59.3)	24 (85.7)	4.1 (1.3 - 13.4)	0.01
SBP development, n ()	2 (3.4)	1 (3.6)	1.1 (0.09 - 12.2)	1.00
Primary prophylaxis with any anti-ammonium drug, n ()	49 (83%)	16 (57.1%)	0.2 (0.09 - 0.7)	0.009
Gastric variceal bleeding source, n ()	9 (15.3%)	3 (10.7%)	0.7 (0.2 - 2.7)	0.74

CI: confidence interval; HE: hepatic encephalopathy; OR: odds ratio; SBP: spontaneous bacterial peritonitis.
Statistical significance: P ≤ 0.05. Risk factor. Protective factor.