| | ALT normalization | | | | | | |
| | NA | | | | | | | | 2.59 (0.70, 6.09) | NA add-on PEG IFN | | | | | | | 1.07 (0.41, 2.82) | 0.42 (0.11, 2.32) | PEG IFN | | | | | | 0.55 (0.22, 1.32) | 0.21 (0.06, 1.07) | 0.51 (0.21, 1.14) | PEG IFN add-on NA | | | | | 1.47 (0.46, 3.22) | 0.56 (0.14, 2.52) | 1.34 (0.39, 3.54) | 2.64 (0.72, 7.73) | PEG IFN combined NA | | | | 9.68 (2.59, 41.22) | 3.80 (0.84, 27.37) | 9.00 (1.83, 51.79) | 18.05 (3.64, 109.82) | 6.76 (1.49, 43.48) | NA switch PEG IFN | | | 2.49 (0.80, 6.49) | 0.95 (0.26, 4.86) | 2.32 (0.65, 7.42) | 4.59 (1.26, 15.25) | 1.71 (0.80, 4.32) | 0.26 (0.04, 1.26) | PEG IFN combined PLA |
| | HBV DNA undetectable | | | | | | |
| | NA | | | | | | | | 0.59 (0.17, 2.27) | NA add-on PEG IFN | | | | | | | 1.25 (0.40, 5.05) | 2.09 (0.38, 13.95) | PEG IFN | | | | | | 0.74 (0.26, 3.21) | 1.24 (0.25, 8.88) | 0.59 (0.20, 2.04) | PEG IFN add-on NA | | | | | 0.26 (0.07, 0.91) | 0.44 (0.07, 2.52) | 0.21 (0.04, 0.74) | 0.35 (0.06, 1.38) | PEG IFN combined NA | | | | 21.11 (2.90, 262.11) | 36.56 (3.27, 567.15) | 17.12 (1.47, 248.25) | 28.69 (2.31, 404.85) | 82.47 (8.49, 1406.85) | NA switch PEG IFN | 13.49 (1.21, 236.27) | | 1.64 (0.37, 6.51) | 2.71 (0.36, 17.18) | 1.30 (0.20, 5.62) | 2.16 (0.29, 9.75) | 6.23 (1.91, 19.45) | | PEG IFN + Placebo |
| | HBeAg loss | | | | | | |
| | NA | | | | | | | | 0.52 (0.10, 2.73) | NA add-on PEG IFN | | | | | | | 0.63 (0.11, 3.29) | 1.21 (0.11, 11.91) | PEG IFN | | | | | | 0.68 (0.15, 2.75) | 1.31 (0.14, 11.60) | 1.09 (0.25, 4.64) | PEG IFN add-on NA | | | | | 0.75 (0.10, 5.48) | 1.46 (0.11, 19.44) | 1.19 (0.09, 17.27) | 1.11 (0.10, 13.48) | PEG IFN combined NA | | | | 0.81 (0.10, 6.95) | 1.57 (0.11, 22.91) | 1.31 (0.09, 21.36) | 1.19 (0.10, 16.22) | 1.08 (0.06, 21.17) | NA switch PEG IFN | | | 1.47 (0.08, 25.96) | 2.83 (0.11, 76.01) | 2.37 (0.08, 64.49) | 2.15 (0.08, 52.38) | 1.93 (0.26, 15.12) | 1.80 (0.05, 62.85) | PEG IFN combined PLA |
| | HBeAg seroconversion | | | | | | |
| | NA | | | | | | | | 0.39 (0.08, 1.86) | NA add-on PEG IFN | | | | | | | 0.53 (0.13, 2.25) | 1.34 (0.16, 12.44) | PEG IFN | | | | | | 0.81 (0.21, 3.14) | 2.09 (0.27, 16.73) | 1.52 (0.39, 5.86) | PEG IFN add-on NA | | | | | 0.55 (0.12, 2.26) | 1.40 (0.15, 12.65) | 1.04 (0.20, 4.88) | 0.69 (0.11, 3.79) | PEG IFN combined NA | | | | 0.37 (0.04, 2.91) | 0.94 (0.07, 13.35) | 0.69 (0.05, 8.63) | 0.45 (0.04, 5.23) | 0.67 (0.05, 9.14) | NA switch PEG IFN | | | 0.62 (0.11, 3.00) | 1.55 (0.16, 15.37) | 1.17 (0.17, 7.39) | 0.76 (0.10, 5.06) | 1.12 (0.30, 4.32) | 1.68 (0.10, 24.88) | PEG IFN combined PLA |
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