Research Article
Association between Serum Uric Acid and Non-Alcoholic Fatty Liver Disease according to Different Menstrual Status Groups
Table 1
Characteristics of participants according to the status of NAFLD in different menstrual statuses.
| | Characteristics | Total | Menstrual period (n = 3404) | | Menopause transition period (n = 724) | | Postmenopausal period (n = 1915) | | | With NAFLD | Without NAFLD | With NAFLD | Without NAFLD | With NAFLD | Without NAFLD |
| | N, (%) | 6043 | 824 (41.0) | 2580 (64.0) | | 244 (12.1) | 480 (11.9) | | 941 (46.8) | 974 (24.1) | | | Age (years) | 45.9 ± 12.8 | 41.5 ± 9.6 | 37.2 ± 8.9 | <0.001 | 48.1 ± 6.9 | 44.8 ± 0.3 | <0.001 | 60.1 ± 7.3 | 58.7 ± 8.5 | <0.001 | | Education level, n (%) | | | | <0.001 | | | 0.023 | | | 0.042 | | Illiteracy/primary | 385 (6.4) | 21 (2.6) | 26 (1.0) | | 11 (4.5) | 12 (2.5) | | 168 (17.9) | 147 (15.1) | | | Middle school | 2991 (49.5) | 381 (46.2) | 857 (33.2) | | 147 (60.3) | 252 (52.5) | | 668 (71.0) | 686 (70.4) | | | College or above | 2667 (44.1) | 422 (51.2) | 1697 (65.8) | | 86 (35.3) | 216 (45.0) | | 105 (11.2) | 141 (14.5) | | | Income, ¥/month, n (%) | | | | <0.001 | | | 0.486 | | | 0.332 | | ≤¥3000 | 3590 (59.4) | 440 (53.4) | 1164 (45.1) | | 157 (64.3) | 292 (60.8) | | 750 (79.7) | 787 (80.8) | | | ¥3001–5000 | 2130 (35.3) | 336 (40.8) | 1230 (47.7) | | 75 (30.7) | 155 (32.3) | | 173 (18.4) | 161 (16.5) | | | >¥5000 | 323 (5.3) | 48 (5.8) | 186 (7.2) | | 12 (4.9) | 33 (6.9) | | 18 (1.9) | 26 (2.7) | | | BMI (kg/m2) | 23.9 ± 3.6 | 26.3 ± 3.6 | 22.3 ± 2.8 | <0.001 | 26.8 ± 3.6 | 22.9 ± 2.7 | <0.001 | 26.6 ± 3.3 | 23.4 ± 2.8 | <0.001 | | Hypertension, n (%) | 1632 (27.0) | 264 (32.0) | 229 (8.9) | <0.001 | 101 (41.4) | 77 (16.0) | <0.001 | 567 (60.3) | 394 (40.5) | <0.001 | | Diabetes, n (%) | 418 (6.9) | 82 (9.9) | 28 (1.1) | <0.001 | 22 (9.0) | 15 (3.1) | <0.001 | 180 (19.1) | 91 (9.3) | <0.001 | | Hyperlipemia, n (%) | 2001 (33.1) | 369 (44.8) | 363 (14.1) | <0.001 | 128 (52.46) | 115 (24.0) | <0.001 | 609 (64.7) | 417 (42.8) | <0.001 | | Total cholesterol (mmol/L) | 4.6 ± 1.0 | 4.6 ± 0.9 | 4.2 ± 0.8 | <0.001 | 4.7 ± 0.9 | 4.6 ± 1.0 | 0.106 | 5.3 ± 1.1 | 5.1 ± 0.9 | 0.004 | | Triglyceride (mmol/L) | 1.4 ± 1.1 | 1.8 ± 1.2 | 1.1 ± 0.8 | <0.001 | 1.8 ± 1.2 | 1.2 ± 0.9 | <0.001 | 2.0 ± 1.5 | 1.4 ± 0.8 | <0.001 | | HDL-C (mmol/L) | 1.4 ± 0.4 | 1.3 ± 0.3 | 1.4 ± 0.4 | <0.001 | 1.4 ± 0.4 | 1.5 ± 0.4 | <0.001 | 1.4 ± 0.4 | 1.6 ± 0.4 | <.0001 | | LDL-C (mmol/L) | 2.5 ± 0.7 | 2.5 ± 0.6 | 2.2 ± 0.6 | <0.001 | 2.6 ± 0.6 | 2.4 ± 0.7 | 0.002 | 2.9 ± 0.7 | 2.7 ± 0.7 | <0.001 | | Waist circumference (cm) | 82.4 ± 10.1 | 87.6 ± 9.6 | 77.8 ± 8.6 | <0.001 | 89.1 ± 8.8 | 79.1 ± 8.5 | <0.001 | 90.3 ± 8.9 | 82.5 ± 8.6 | <0.001 |
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NAFLD: non-alcohol fatty liver disease; SUA: blood uric acid; BMI: body mass index HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.
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