Clinical Study

A Randomized Placebo-Controlled N-of-1 Trial: The Effect of Proton Pump Inhibitor in the Management of Gastroesophageal Reflux Disease

Table 3

Results for treatment comparisons of the N-of-1 trial (12 pairs of treatments, 24 weeks).

Weeks of treatmentMean-controlled symptoms (GerdQ)Standard deviationD'Agostino–PearsonWilcoxon test value

Treatment A (±SD)129.500.50.5980.30078
Treatment B (±SD)1210.170.60.035

GerdQ: gastroesophageal reflux disease questionnaire.