|
| No | Year | Author | Population | Age | Sex | Clinical Presentation | Ulcer | Location | Size (cm) | Diagnosis | Treatment | Prognosis |
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| 1[1] | 2007 | Takahashi | Japan | 50 | M | acute abdominal pain (perforation) | + | pyloric antrum | 4 × 4 × 2.5 | PAMT | distal gastrectomy | NA |
|
| 2[1] | 2007 | Takahashi | Japan | 68 | M | incidental | - | pyloric antrum | 4.5 × 3.5 × 3.0 | PAMT | partial gastrectomy | uneventful for 12 months |
|
| 3[17] | 2008 | Galant | Belgium | 61 | M | hematemesis | erosion | antrum | 3.7 | PAMT | partial gastrectomy | uneventful for 6 months |
|
| 4[18] | 2008 | Rau | Germany | 50 | F | morning nausea | + | antrum | 1.9 × 1.8 × 0.8 | PAMT | Median laparotomy and local excision | No recurrence for 3 months |
|
| 5[9] | 2008 | Yoshida | USA | 19 | F | mass in the stomach | - | antrum | 4.5 × 3.5 × 3.0 | PAMT | distal gastrectomy | uneventful for 9 months |
|
| 6[9] | 2008 | Yoshida | USA | 46 | M | upper gastrointestinal bleeding | + | antrum | 3.5 | PAMT | distal gastrectomy | uneventful for 4 months |
|
| 7[11] | 2009 | Miettinen | USA | 38 | F | upper gastrointestinal bleeding, ulcer | + | antrum, lesser curvature | 3 × 2 | PF | distal gastrectomy | lost f/u |
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| 8[11] | 2009 | Miettinen | USA | 62 | M | progressive weight loss for months | - | antrum, pyloric | 4 × 4 | PF | partial gastrectomy, omentectomy | lost f/u |
|
| 9[11] | 2009 | Miettinen | USA | 75 | F | unknown | + | antrum, serosa | 5 | PF | subtotal gastrectomy | died of unknown cause, 2 months |
|
| 10[11] | 2009 | Miettinen | USA | 65 | F | weight loss, gastric ulcer | + | antrum, lesser curvature, duodenal bulb | 5 × 4.5 × 2.5 | PF | partial gastrectomy | died of unknown cause, 14.5 years |
|
| 11[11] | 2009 | Miettinen | USA | 33 | M | anemia, weakness | + | antrum, anterior wall | 5.5 × 3.5 × 3.5 | PF | 50% distal gastrectomy | alive without disease for 19.7 years |
|
| 12[11] | 2009 | Miettinen | USA | 43 | M | gastrointestinal bleeding | + | antrum, near pylorus | 5.5 × 4.5 × 4.5 | PF | partial gastrectomy | alive without disease for 18.4 years |
|
| 13[11] | 2009 | Miettinen | USA | 56 | F | unknown | - | pylorus, duodenal bulb | 5.5+3 | PF | partial gastrectomy | alive without disease for 19.9 years |
|
| 14[11] | 2009 | Miettinen | USA | 50 | M | gastric outlet obstruction | - | antrum, duodenal bulb | 7 × 6 × 6 | PF | distal gastrectomy | died of unknown cause, 25.5 years |
|
| 15[11] | 2009 | Miettinen | USA | 21 | M | syncope, anemia | + | antrum, prepyloric, duodenal bulb | 9 × 6 × 5 | PF | antrectomy, B1-reconstruction | alive with unknown status for 22 years |
|
| 16[11] | 2009 | Miettinen | USA | 16 | F | hematemesis | + | antrum, pylorus | 10 × 9 × 6 | PF | distal gastrectomy | alive with unknown status for 3 years |
|
| 17[11] | 2009 | Miettinen | USA | 30 | F | nonhealing gastric ulcer | + | antrum | 10 × 9 × 6 | PF | distal gastrectomy | alive without disease for 9 years, alive with unknown status for 24 years |
|
| 18[11] | 2009 | Miettinen | USA | 7 | F | emesis, diarrhea, protruding abdominal mass | - | antrum, pylorus, duodenal bulb | 15 × 11 × 8 | PF | excision of tumor, gastric wall resection at the tumor attachment | lost f/u |
|
| 19[19] | 2009 | Pailoor | Malaysia | 23 | F | melena | + | antrum | 8.0 × 4.0 | PAMT | partial gastrectomy | uneventful for 2 months |
|
| 20[20] | 2010 | Sing | South Africa (Indian) | 35 | F | cushingoid appearance, amenorrhea | - | pyloro-antral region, anterior wall of the greater curvature | 4 × 3 × 2 | PAMT | exploratory laparotomy and wide local excision | uneventful for 12 months |
|
| 21[10] | 2010 | Takahashi | Japan | 23 | M | abdominal pain, abdominal discomfort, melena | + | antrum, duodenal bulb | 14 × 14 × 7 | PAMT | partial gastrectomy | uneventful for 12 months |
|
| 22[21] | 2010 | Tan | Australia (Filipino) | 34 | M | abdominal mass, abdominal discomfort, decreased appetite (perforation) | + | antrum | 3.5 × 3.4 × 2.5 | PAMT | distal gastrectomy | uneventful for 2 months |
|
| 23[22] | 2010 | Wang | China | 54 | F | abdominal distension, heartburn, hiccup, regurgitation, loss of appetite | erosion | fundus | 1.5 × 1.2 | PAMT | endoscopic resection | uneventful for 6 months |
|
| 24[23] | 2010 | Cooper | USA | 64 | M | epigastric pain | NA | antrum | 4.0 × 2.0 | PAMT | laparoscopic excision | uneventful for 3 years |
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| 25[24] | 2010 | Cui | China | 54 | F | abdominal distension, decreased appetite | erosion | fundus | 0.8 | PAMT | NA | NA |
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| 26[14] | 2011 | Kim | Korea | 52 | M | dyspepsia | + | antrum | 3.5 × 2.3 | PAMT | laparoscopic wedge resection | uneventful for 5 months |
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| 27[25] | 2012 | Kang | Korea | 47 | M | incidental | + | mid body, posterior wall and greater curvature | 3 × 2 | PAMT | wedge resection | uneventful for 6 years |
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| 28[25] | 2012 | Kang | Korea | 63 | F | incidental | + | lower body, greater curvature | 2.2 × 1.6 | PAMT | endoscopic resection | uneventful for 1 month |
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| 29[26] | 2012 | Schulz | Germany | 59 | M | heartburn, upper abdominal pain | + | pylorus | 1.5 | PAMT | combined laparoscopic endoscopic local resection | NA |
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| 30[27] | 2012 | Cai | China | 32 | M | incidental | NA | antrum | | PF | distal gastrectomy | NA |
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| 31[27] | 2012 | Cai | China | 47 | F | upper abdominal pain | NA | antrum | | PF | radical distal gastrectomy | NA |
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| 32[28] | 2012 | Wang | China | 12 | M | gastrointestinal bleeding | NA | antrum | | PF | partial gastrectomy | uneventful for 84 months |
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| 33[29] | 2012 | Miettinen | USA | 49 | F | NA | NA | antrum | 3.5 × 2.5 × 2.5 | PF | wedge resection | NA |
|
| 34[30] | 2012 | Li | China | 47 | F | epigastric discomfort, abdominal pain | - | antrum | 5 × 3 × 2 | PAMT | laparoscopic distal gastrectomy | uneventful for 1.5 years |
|
| 35[31] | 2012 | Bi | China | 31 | M | Abdominal pain | - | Antrum | 8.0 | PAMT | NA | NA |
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| 36[31] | 2012 | Bi | China | 47 | F | Abdominal pain | + | Antrum | 4.5 | PAMT | NA | NA |
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| 37[31] | 2012 | Bi | China | 42 | F | Abdominal distension | - | Antrum | 4.6 | PAMT | NA | NA |
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| 38[32] | 2013 | Kao | China | 53 | F | Abdominal distension, abdominal pain, nausea, acid regurgitation | NA | NA | NA | PAMT | NA | NA |
|
| 39[33] | 2014 | Baek | Korea | 38 | F | incidental | + | upper body, posterior wall and greater curvature | 3.5 × 2.3 | PAMT | wedge resection | uneventful for 6 months |
|
| 40[34] | 2014 | Duckworth | USA | 16 | F | chest pain, shortness of breath, finger numbness | NA | posterior mediastinum near the esophagus at the level of the carina | 3.2 | PF | thoracoscopic resection | uneventful for 14 months |
|
| 41[34] | 2014 | Duckworth | USA | 11 | F | severe iron-deficiency anemia | + | pylorus | 3.5 | PF | laparoscopic distal gastrectomy | uneventful for 15 months |
|
| 42[35] | 2014 | Ikemura | Japan | 27 | F | epigastric pain, melena, anemia | + | antrum of the lesser curvature side | 4.6 × 3.0 × 2.8 | PAMT | partial gastrectomy | uneventful for 40 months |
|
| 43[36] | 2014 | Lee | Hong Kong (Filipino) | 42 | F | abdominal pain, fever, anemia (fistulating abscess formation) | + | antrum | 12.9 × 11.9 × 10.6 | PF | distal gastrectomy | uneventful for 3 weeks |
|
| 44[37] | 2014 | Li | Chinese | 32 | M | incidental | - | antrum, anterior wall | 3.4 × 3.0 | PAMT | partial gastrectomy | uneventful for 3 years |
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| 45[38] | 2014 | Sakamoto | Japan | 60 | M | epigastralgia | + | antrum | 2 | PF | laparoscopic partial gastrectomy | uneventful for 12 years |
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| 46[39] | 2014 | Li | China | 73 | F | upper abdominal pain | NA | antrum | | PF | partial gastrectomy | NA |
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| 47[40] | 2014 | Tian | China | 64 | M | upper abdominal discomfort | - | antrum | 3.3 × 2.5 | PF | distal gastrectomy | uneventful for 6 months |
|
| 48[41] | 2015 | Banerjee | India | 19 | F | dull upper abdominal pain, lump in the right hypochondrium | + | duodenum (D1), posterior | 13.8 × 8.6 | PAMT | distal gastrectomy, proximal duodenectomy, Billroth II gastrojejunostomy | uneventful for 6 months |
|
| 49[42] | 2015 | Fassan | Italy (Caucasian) | 55 | F | cholelithiasis | NA | gallbladder | 1 | PF | laparoscopic cholecystectomy | no postsurgical complication |
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| 50[43] | 2015 | Lu | China | 26 | F | progressive abdominal distension, nausea, vomiting, melena | NA | antrum | NA | PAMT | distal gastrectomy | NA |
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| 51[44] | 2015 | Ni | China | 21 | F | melena, dizziness, anemia | + | antrum, greater curvature | 4 × 3 × 3 | PF | distal gastrectomy | uneventful for 3 years |
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| 52[45] | 2015 | Wei | China | 50 | F | upper abdominal pain | NA | antrum | | PF | subtotal gastrectomy | uneventful for 3 months |
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| 53[46] | 2015 | Yue | China | 34 | M | upper abdominal pain | NA | antrum | | PF | distal gastrectomy | uneventful for 24 months |
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| 54[46] | 2015 | Yue | China | 50 | F | upper abdominal pain | NA | antrum | | PF | subtotal gastrectomy | uneventful for 3 months |
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| 55[47] | 2015 | Xu | China | 50 | F | abdominal pain | NA | gastric body | 3 × 2 | PAMT | Total gastrectomy | uneventful for 6 months |
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| 56[15] | 2016 | Dixit | India | 51 | F | abdominal pain, vomiting, weight loss (with synchronous ovarian neoplasms) | + | pylorus | 8.4 × 6.1 × 5 | PAMT | distal gastrectomy | no postsurgical complication |
|
| 57[48] | 2016 | Inoue | Japan | 36 | F | epigastric pain, anemia | + | antrum | 2.5 × 2.2 × 2.0 | PF | radical resection with laparoscopic endoscopic cooperative surgery | uneventful for unknown period |
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| 58[49] | 2016 | Jonaitis | Lithuania (Caucasian) | 28 | F | epigastric pain associated with meals, iron-deficiency anemia, weight loss | + | antrum, anterior wall | 3 | PAMT | partial gastrectomy of the Billroth I type | follow-up not reported; gastroduodenal anastomositis, resolved with conservative treatment |
|
| 59[50] | 2016 | Kane | USA (Vietnamese) | 28 | F | acute, severe abdominal pain and worsening anemia | + | antrum | 5.5 × 3.5 | PF | distal gastrectomy with a Roux-en-Y gastrojejunostomy | dyspepsia 23 months thereafter, otherwise uneventful for 23 months (only moderate stenosis of anastomosis) |
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| 60[51] | 2016 | Morris | USA | 9 | F | intermittent abdominal pain, nausea, vomiting, weight loss | + | antrum, posterior | 5 | PF | laparotomic anterior gastrotomy with tumor resection | uneventful for 6 months |
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| 61[52] | 2016 | Nagahisa | Japan | 39 | M | epigastric pain | + | antrum, anterior wall | 3.5 × 3 | PAMT | partial gastrectomy with laparoscopic endoscopic cooperative surgery | uneventful for 9 months |
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| 62[53] | 2016 | Quero | Italy | 47 | M | syncope, regurgitation, epigastric discomfort | + | antrum | 6.5 | PAMT | distal gastrectomy | uneventful for 10 months |
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| 63[54] | 2016 | Spans | Belgium | 19 | M | NA | NA | antrum | 5.5 | PF | NA | NA |
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| 64[54] | 2016 | Spans | Belgium | 65 | F | NA | NA | antrum | 4.3 × 3.0 × 1.7 | PF | NA | NA |
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| 65[54] | 2016 | Spans | Belgium | 58 | F | NA | NA | antrum | NA | PF | NA | NA |
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| 66[54] | 2016 | Spans | Belgium | 51 | F | NA | NA | antrum | 9.0 × 8.5 × 5.5 | PF | NA | NA |
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| 67[54] | 2016 | Spans | Belgium | 63 | F | NA | NA | jejunum, proximal | 3.5 × 3.0 × 2.0 | PF | NA | NA |
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| 68[54] | 2016 | Spans | Belgium | 76 | F | NA | NA | stomach | 4 | PF | NA | NA |
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| 69[54] | 2016 | Spans | Belgium | 62 | F | NA | NA | stomach | NA | PF | NA | NA |
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| 70[54] | 2016 | Spans | Belgium | 30 | F | NA | NA | stomach | 2 | PF | NA | NA |
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| 71[54] | 2016 | Spans | Belgium | 28 | M | NA | NA | gastric body | 10 × 6 × 3 | PF | NA | NA |
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| 72[54] | 2016 | Spans | Belgium | 44 | F | NA | NA | stomach | NA | PF | NA | NA |
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| 73[54] | 2016 | Spans | Belgium | 18 | F | NA | NA | antrum | 4.5 × 3.5 × 2.7 | PF | NA | NA |
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| 74[54] | 2016 | Spans | Belgium | 19 | F | NA | NA | stomach | 4.5 | PF | NA | NA |
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| 75[54] | 2016 | Spans | Belgium | 46 | M | NA | NA | antrum | 3.5 | PF | NA | NA |
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| 76[54] | 2016 | Spans | Belgium | 29 | M | NA | NA | antrum | 6.5 × 4.5 × 4.0 | PF | NA | NA |
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| 77[54] | 2016 | Spans | Belgium | 36 | F | NA | NA | antrum | 8 | PF | NA | NA |
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| 78[54] | 2016 | Spans | Belgium | 47 | F | NA | NA | antrum | 4.5 × 3.7 | PF | NA | NA |
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| 79[55] | 2016 | Li | China | 11 | M | upper abdominal discomfort | NA | antrum | | PF | partial gastrectomy | uneventful for 12 months |
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| 80[56] | 2016 | Li | Chinese | 44 | F | incidental | - | antrum | 0.8 × 0.8 | PAMT | endoscopic submucosal dissection | uneventful for 6 months |
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| 81[57] | 2016 | Zhang | China | 48 | M | upper abdominal pain | NA | antrum | | PF | partial gastrectomy | uneventful for 12 months |
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| 82[16] | 2017 | Akai | Japan | 55 | M | incidental | NA | gastric angle | 1.7 | PAMT | laparoscopic partial gastrectomy | NA |
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| 83[58] | 2017 | Gonzalez-Cordero | Spain | 37 | M | upper gastrointestinal bleeding with hemodynamic instability | NA | antrum | 5.8 × 5 × 4 | PF | antrectomy | uneventful postoperatively |
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| 84[59] | 2017 | Hu | China | 26 | M | abdominal distension | + | fundus | 1.8 | PF | endoscopic submucosal dissection | uneventful for 32 months |
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| 85[59] | 2017 | Hu | China | 31 | F | abdominal distension | - | antrum | 2.5 | PF | endoscopic submucosal dissection | NA |
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| 86[59] | 2017 | Hu | China | 72 | F | abdominal distension | + | antrum | 7 | PF | distal subtotal gastrectomy | uneventful for 56 months |
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| 87[59] | 2017 | Hu | China | 59 | F | abdominal distension | + | antrum | 2.5 | PF | distal subtotal gastrectomy | uneventful for 68 months |
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| 88[59] | 2017 | Hu | China | 52 | M | incidental | + | fundus | 1.2 | PF | endoscopic submucosal dissection | uneventful for 24 months |
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| 89[59] | 2017 | Hu | China | 59 | F | melena, anemia | + | antrum | 3 | PF | distal subtotal gastrectomy | uneventful for 40 months |
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| 90[59] | 2017 | Hu | China | 48 | M | abdominal distension | + | antrum | 3 | PF | distal subtotal gastrectomy | uneventful for 95 months |
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| 91[59] | 2017 | Hu | China | 58 | M | abdominal pain | + | antrum | 3.5 | PF | distal subtotal gastrectomy | uneventful for 34 months |
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| 92[59] | 2017 | Hu | China | 46 | M | abdominal distension | - | antrum | 4 | PF | distal subtotal gastrectomy | uneventful for 65 months |
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| 93[59] | 2017 | Hu | China | 40 | F | melena, anemia | + | antrum | 3.8 | PF | distal subtotal gastrectomy | uneventful for 70 months |
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| 94[60] | 2017 | Kawara | Japan | 66 | M | gastric tumor | - | antrum | 4 × 3 | PF | endoscopic submucosal dissection | uneventful for 12 months |
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| 95[61] | 2017 | Kim | Korea | 51 | M | incidental | - | antrum, lesser curvature | 2.0 × 1.5 | PAMT | laparoscopic gastric wedge resection | uneventful for 3 years |
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| 96[62] | 2017 | Liang | China | 11 | M | right epigastric discomfort with episodic pain | - | pylorus, anterior | 17 × 10.5 × 5 | PAMT | partial gastrectomy | uneventful for 12 months |
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| 97[63] | 2017 | Moris | USA | 63 | M | upper gastrointestinal bleeding, anemia, melena | NA | duodenum | 3 × 3 | PF | pancreas-preserving duodenectomy of the first 2 portions | uneventful for 20 months, complicated only by a low output pancreatic skin fistula totally drained after 4 months |
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| 98[64] | 2017 | Qi | China | 42 | M | melena | + | antrum, greater curvature | 3 × 2 × 1.8 | PF | laparoscopic partial gastrectomy | uneventful for 12 months |
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| 99[64] | 2017 | Qi | China | 66 | M | epigastric pain | - | antrum, greater curvature | 2 × 1 × 0.7 | PF | endoscopic submucosal dissection | uneventful for 12 months |
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| 100[65] | 2017 | Szurian | Austria (Caucasian) | 16 | F | anemia, nausea | + | antrum, anterior wall | 6.5 | PF | distal gastrectomy and retrocolic gastrojejunostomy (Billroth II) | pulmonary embolism postoperatively and discharged on day 9, otherwise uneventful for 6 months |
|
| 101[65] | 2017 | Szurian | Austria | 34 | M | epigastric discomfort, flatulence | + | pylorus | 1.6 | PF | distal gastrectomy and retrocolic gastrojejunostomy (Billroth II) | uneventful for 16 months |
|
| 102[66] | 2017 | Wambura | Tanzania (Tanzanian) | 41 | F | anemia, epigastric discomfort, melena | + | antrum | 5.5 × 5 | PF | distal gastrectomy with Roux-en-Y gastrojejunostomy | uneventful for 12 months |
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| 103[67] | 2017 | Yang | China | 50 | F | abdominal pain | - | gastric upper body | 15 × 10 | PF | laparoscopic partial gastrectomy | uneventful for 2 years |
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| 104[68] | 2017 | Zhou | China | 51 | M | epigastric discomfort, heartburn | NA | antrum, greater curvature | 4 × 3 × 1.8 | PF | total resection | uneventful for 15 months |
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| 105[69] | 2017 | Wang | China | 66 | F | Abdominal pain, melena, dizziness, abdominal distension | erosion | Antrum | 3 | PF | NA | NA |
|
| 106[70] | 2018 | Djurić | Serbia | 14 | M | iron-deficiency anemia, fatigue, epigastric pain | NA | Antrum | NA | PF | partial gastrectomy | NA |
|
| 107[71] | 2018 | Jang | Korea | 47 | F | heartburn | - | pylorus | 2.5 × 2.0 | PF | antrectomy with Billroth I anastomosis | uneventful for 7 months |
|
| 108[72] | 2018 | Rohit | USA | 81 | F | weight loss of 3.6 kg in 3 months | NA | gastric body, lesser curvature | 2.7 × 2.4 | PF | non-surgical follow-up | symptom resolved 3 months after |
|
| 109[73] | 2018 | Wang | Chinese | 52 | F | upper abdominal pain | + | mid gastric body, greater curvature | 1.5 × 1.0 × 1.0 | PF | gastroscope-assisted laparoscopic wedge resection | uneventful for 10 months |
|
| 110[74] | 2018 | Zhang | China | 31 | F | hematochezia, syncope, upper gastrointestinal bleeding, anemia | + | upper segment of jejunum | 1.2 × 1.0 | PF | exploratory laparotomy and resection of the upper jejunal tumor and local intestine | uneventful for 3 years |
|
| 111 | 2019 | Wu | Taiwan (Taiwanese) | 59 | F | acid regurgitation | - | antrum | 2 × 1.2 × 1.2 | PF | partial gastrectomy | uneventful for 20 months |
|
| 112[75] | 2019 | Fukazawa | Japan | 14 | F | abdominal pain, hematemesis | + | antrum | | PF | partial gastrectomy | uneventful for 16 months |
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| 113[76] | 2019 | Banerjee | USA | 65 | M | anemia, early satiety, dyspepsia, hematemesis | + | antrum | 5 × 2.3 | PF | wedge resection | NA |
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| 114[77] | 2019 | Lai | USA | 21 | F | NA | NA | gastric body | | PF | partial gastrectomy | 4 years |
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| 115[77] | 2019 | Lai | USA | 42 | F | NA | + | antrum | | PF | partial gastrectomy | 4 years |
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| 116[77] | 2019 | Lai | USA | 79 | F | NA | NA | antrum | | PF | partial gastrectomy | 1 year |
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| 117[77] | 2019 | Lai | USA | 33 | M | NA | NA | antrum | | PF | partial gastrectomy | 11 years |
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| 118[77] | 2019 | Lai | USA | 60 | M | NA | NA | antrum | | PF | partial gastrectomy | 1 year |
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| 119[77] | 2019 | Lai | USA | 77 | M | NA | NA | gastric body | | PF | partial gastrectomy | 2 years |
|
| 120[77] | 2019 | Lai | USA | 45 | M | NA | NA | antrum | | PF | only endoscopic biopsy | 0.2 years |
|
| 121[78] | 2019 | Li | China | 5 | M | pale complexion | NA | antrum | 8.2 × 7.5 × 5.5 | PF | distal gastrectomy | 36 months |
|
