Research Article

Diospyros kaki and Citrus unshiu Mixture Improves Disorders of Lipid Metabolism in Nonalcoholic Fatty Liver Disease

Table 3

The effects of PCM on serum hepatic functional parameters.

GroupNormalHFD-fed mice
VehO60PCM50PCM100

AST (IU/L)59.23 ± 4.22155.47 ± 18.93108.80 ± 7.7587.08 ± 4.9579.86 ± 10.28
ALT (IU/L)16.41 ± 1.1436.38 ± 4.1315.93 ± 1.2216.73 ± 0.6717.55 ± 1.12

Veh, HFD control mice; O60, orlistat 60 mg/kg-treated and obese mice; PCM50, PCM 50 mg/kg-treated and obese mice; PCM100, PCM 100 mg/kg-treated and obese mice. Data are the mean ± SEM, n = 7. Significance:  < 0.05,  < 0.01, and  < 0.001 versus HFD control mice.