Research Article

Association and Prediction of Subclinical Atherosclerosis by Nonalcoholic Fatty Liver Disease in Asymptomatic Patients

Table 1

General characteristics of the study population.

Without significant stenosis (n = 3,449) (mean ± SD)With significant stenosis (n = 244) (mean ± SD)value

Sex (N, %)<0.001
 Male1.800 (52.18)170 (69.67)
 Female1.649 (47.81)74 (30.32)<0.001

Age (years)57.00 ± 9.6763.58 ± 8.69<0.001
BMI (kg/m2)24.14 ± 3.2124.74 ± 2.870.004
WC (cm)85.96 ± 9.0988.58 ± 7.97<0.001
SBP (mmHg)125.40 ± 15.94130.01 ± 15.61<0.001
DBP (mmHg)75.58 ± 10.6577.07 ± 11.320.035
HbA1c5.86 ± 0.686.26 ± 1.08<0.001
FPG (mg/dL)96.07 ± 20.29109.52 ± 31.26<0.001
TC (mg/dL)199.56 ± 36.96199.95 ± 37.460.871
TG (mg/dL)115.78 ± 67.86138.89 ± 97.39<0.001
HDL (mg/dL)54.60 ± 14.4749.26 ± 12.62<0.001
LDL (mg/dL)126.85 ± 34.94129.69 ± 38.280.222
AST (IU/L)25.74 ± 14.4827.55 ± 14.160.059
ALT (IU/L)27.52 ± 24.6731.42 ± 27.490.017
γ-GTP (IU/L)32.79 ± 33.6838.03 ± 42.830.021
Hypertension (%)1247  (36.15)146  (59.83)<0.001
Current smoker (%)458  (13.27)51  (20.90)<0.001

NAFLD (N, %)<0.001
 Normal (grade 0)2,005  (58.13)99  (40.57)
 Mild (grade 1)710  (20.58)67  (27.45)
 Moderate (grade 2)657  (19.04)67  (27.45)
 Severe (grade 3)76  (2.23)11  (4.50)

SD: standard deviation; BM: body mass index; WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; TC: total cholesterol; TG: triglyceride; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein cholesterol; AST: aspartate aminotransferase; ALT: alanine aminotransferase; γ-GTP: γ-glutamyltranspeptidase; NAFLD: nonalcoholic fatty liver disease. Log transformation t test.