Risk of Hepatocellular Carcinoma Remains High in Patients with HBV-Related Decompensated Cirrhosis and Long-Term Antiviral Therapy

Table 2

Risk factors for HCC development in patients with hepatitis B virus-related decompensated cirrhosis.

Variables	Univariate analysis		Multivariate analysis
	OR (95% CI)	value	OR (95% CI)	value
Age	2.994 (1.240–7.227)	0.02	2.987 (1.301–6.858)	0.01
Sex	2.561 (1.055–6.220)	0.04	2.408 (1.126–5.149)	0.02
ALT (U/L)	0.996 (0.987–1.005)	0.35
Total bilirubin (μmol/L)	1.006 (0.987–1.026)	0.54
Cholinesterase (U/L)	1.000 (0.999–1.000)	0.50
Platelet counts (E + 09/L)	1.000 (0.994–1.007)	0.89
INR	0.408 (0.062–2.674)	0.35
Sodium (mmol/L)	1.122 (0.968–1.301)	0.13
Creatinine (μmol/L)	0.998 (0.978–1.0191)	0.86
AFP (ng/ml)	0.998 (0.998–1.002)	0.77

Abbreviations: ALT, alanine aminotransferase; INR, prothrombin time/international normalized ratio; AFP, alpha-fetoprotein.