Immunohistochemical Differentiation between Western and East Asian Types of CagA-Positive Helicobacter pylori in Gastric Biopsy Samples

Table 2

Detection status of both EPIYA-C and EPIYA-D motifs of H. pylori in gastric biopsy samples by IHC and PCR.

Detection status of both EPIYA-C/D motifs by IHC	Number of samples with the IHC result	Number of samples with detection of both EPIYA-C/D motifs by PCR
		C (+)/D (−)	C (−)/D (+)	C (−)/D (−)	C (+)/D (+)
C (+)/D (−)	27	26	0	1	0
C (−)/D (+)	30	1	27	1	1
C (−)/D (−)	12	3	1	8	0
C (+)/D (+)	0	0	0	0	0

Detection by IHC or PCR was positive (+) or negative (−) for the EPIYA-C (C) or EPIYA-D (D) motif. IHC: immunohistochemistry, Concordance rate of the EPIYA-C/D motif was 88% (Κappa = 0.82, by unweighted Cohen’s kappa coefficient).