Research Article
Comprehensive Analysis of N6-Methyladenosine (m6A) RNA Methylation Regulators and Tumour Microenvironment Cell Infiltration Involving Prognosis and Immunotherapy in Gastroesophageal Adenocarcinomas
Figure 2
Differential overall survival, TIICs, and risk-signature regulators expression of GEA in the cluster 1/2 subgroups. (a) Consensus clustering matrix for k = 2. (b) Consensus clustering cumulative distribution function (CDF) for k = 2–9. (c) Relative change in the area under CDF curve for k = 2–9. (d) Principal component analysis of the total RNA expression profile in TCGA dataset. GEA in the Cluster 1 subgroup are marked with red and the Cluster 2 subgroup is marked with blue. (e) Kaplan–Meier overall survival (OS) curves for patients in the Cluster1/2 subgroup. (f) The differential expression of PD-1 between Cluster 1 and Cluster 2. (g) Vioplot visualizing differentially expressed immune cells between Cluster 1 and Cluster 2 (assume blue is Cluster 1 and red is Cluster 2). GEA: gastroesophageal adenocarcinoma.
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |