Neurosteroid Activation of GABA-A Receptors: A Potential Treatment Target for Symptoms in Primary Biliary Cholangitis?

Figure 3

Symptom severity (none/mild vs. severe) as defined by the PBC-40 questionnaire domains, according to allopregnanolone levels (ng/ml). (a) Cognitive; (b) emotional; (c) itch; (d) fatigue; (e) social; (f) general symptoms.

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(b)

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(f)