Research Article
Neurosteroid Activation of GABA-A Receptors: A Potential Treatment Target for Symptoms in Primary Biliary Cholangitis?
Table 1
Defined scores ranges and cut-offs for PBC-40 domains.
| | PBC -40 domain (number of items) | None | Mild | Moderate | Severe |
| | Cognitive impairment (6) | <6 | 7–15 | 16–21 | >22 | | Emotional (3) | <3 | 4–7 | 8–11 | >12 | | Itch (3) | <3 | 4–8 | 9–11 | >11 | | Fatigue (11) | <11 | 12–28 | 29–39 | >40 | | Social (10) | <10 | 11–28 | 29–40 | >41 | | General symptoms (7) | <7 | 8–18 | 19–25 | >26 |
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