Review Article

Hepatic Disorders and COVID-19: From Pathophysiology to Treatment Strategy

Table 1

The role of inhibitory medications in liver transplantation patients.

MedicationFunction

Calcineurin inhibitorsThe findings show that calcineurin inhibitors have antiviral effects by reducing the cytokine cascade during COVID-19 disease [80, 81].
mTOR inhibitorsOn the other hand, the mTOR inhibitors have a beneficial impact on memory T cell function and inhibit the replication of viruses such as cytomegalovirus, herpes virus-8, Epstein-Barr, and human immunodeficiency virus [82].
MycophenolateAccording to studies, mycophenolate also has a cytostatic impact on activated lymphocytes [83]. Also, it causes an exacerbation of SARS-CoV-2 virus infection [84].