Virological Changes of Chronic Hepatitis B Patients with Minimally Elevated Levels of Alanine Aminotransferase: A Meta-Analysis and Systematic Review

Figure 2

The outcomes of HBsAg loss. (a) Pooled risk ratio for HBsAg loss between the antiviral therapy group and control group. (b) Subgroup analysis stratified by patients’ baseline parameters (the status of HBeAg and the level of HBV DNA). (c) Subgroup analysis stratified by therapeutic regimen with or without IFN. (d) Subgroup analysis stratified by monotherapy and combined therapy (IFN plus NAs). NAs, nucleos(t)ide analogs; IFN, interferon; CI, confidence interval; monotherapy exclusively included NAs or IFN. The size of square represents the weight of each study, and the vertical dotted line represents the pooled rate.

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