Research Article

A Comprehensive Hepatitis B Surface Antigen-Positive Patient-Centered Screening and Linkage to Care Strategies Targeting Microelimination of Hepatitis C Virus Infection in Chongqing, China

Table 1

General demographic characteristics of cases with HBsAg and anti-HCV antibody positive (N = 44).

VariablesNo. of cases %HCV-RNA positive

Sex (n = 44)Male32 (72.7%)14 (82.4%)
Female12 (27.3%)3 (17.6%)

Age (n = 44)21∼301 (2.3%)0 (0%)
31∼407 (15.9%)3 (17.6%)
41∼5023 (52.3%)9 (52.9%)
51∼6010 (22.7%)2 (11.8%)
61∼703 (6.8%)3 (17.6%)

HBV status (n = 44)HBsAg+, HBeAg+, anti-HBc+4 (9.1%)1 (25%)
HBsAg+, HBeAb+, anti-HBc+39 (88.6%)16 (41.0%)
HBsAg+, and anti-HBc+1 (2.3%)0

Duration of HBV therapy in patients receiving anti-HCV therapy (n = 20)Before anti-HCV therapy8
Simultaneously with anti-HCV therapy3
After HCV therapy2
Not start HBV therapy7

Liver cirrhosis status (n = 40)Decompensated cirrhosis10
Compensated cirrhosis7
No liver cirrhosis23

Genotype (n = 21)GT15
GT21
GT36
GT65
No amplification4

Probable infection routes (n = 38)Intravenous drug use10 (26.3%)6 (60.0%)
Blood-borne1 (2.6%)1 (100.0%)
Surgery history13 (34.2%)5 (38.5)
Tooth extraction history1 (2.6%)0
Sexual transmission2 (5.3%)1 (50.0%)
Transfusion8 (21.1%)3
Dental treatment history1 (2.6%)1 (100.0%)
Hemodialysis1 (2.8%)0
Unknown11 (28.9%)2 (18.2%)

Treatment history (n = 20)Others9 (45.0%)
SOF + DCV ± RBV2 (10.0%)
SOF/VEL ± RBV3 (15.0%)
Elbasvir/grazoprevir2 (10.0%)
IFN + RBV1 (5.0%)
SOF + RBV2 (10.0%)
Ledipasvir/sofosbuvir1 (5.0%)

SOF = sofosbuvir; DCV = daclatasvir; VEL = velpatasvir; IFN = interferon; RBV = ribavirin.