The Potential Dual Role of H2.0-like Homeobox in the Tumorgenesis and Development of Colorectal Cancer and Its Prognostic Value

<div><i>HLX</i> could be involved in the immune cell infiltration in CRC patients. (a) The relative proportions of 22 immune infiltrating cells in CRC samples in the TCGA cohort. (b) The content of 22 immune infiltrating cells in high and low <i>HLX</i> expression groups using the CIBERSORT algorithm. The content of B.cells.naive (c) and T.cells.CD8 (d) in high and low <i>HLX</i> expression groups using the Xcell method. (e) The correlation of HLX with 12 immune infiltrating cells. (f) The correlation of HLX with 8 immune checkpoints (PD-1 (PDCD1), CTLA4, PDL-1 (CD274), PDL-2 (PDCD1LG2), CD80, CD86, LAG3, and TIGIT).</div>

Canadian Journal of Gastroenterology and Hepatology

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Figure 6

Figure 6: The Potential Dual Role of H2.0-like Homeobox in the Tumorgenesis and Development of Colorectal Cancer and Its Prognostic Value 