Combined Age with Mean Decrease Rates of Total Bilirubin and MELD Score as a Novel and Simple Clinical Predictor on 90-Day Transplant-Free Mortality in Adult Patients with Acute Liver Failure Undergoing Plasma Exchange: A Single-Center Retrospective Study
Table 1
Baseline and clinical data of adult patients with ALF undergoing PE.
Variable
N
Min
Max
Mean
Std
p25
p50
p75
Age
73
19.00
80.00
48.77
12.85
40.50
48.00
56.00
Height
73
1.52
1.88
1.70
0.09
1.66
1.71
1.76
Weight
73
42.00
110.00
70.67
11.19
62.50
70.00
77.00
BMI
73
14.88
35.84
24.41
3.26
22.45
24.31
26.33
Total bilirubin before PE
73
151.00
850.60
448.35
148.49
354.15
444.90
543.50
Direct bilirubin before PE
73
109.20
686.30
360.44
132.97
257.30
346.00
443.55
Indirect bilirubin before PE
73
1.30
233.80
88.28
52.10
50.35
87.40
117.35
Prothrombin activity before PE
73
13.00
77.00
30.13
12.00
21.00
28.00
35.50
MELD score before PE
73
9.36
48.52
26.67
5.93
22.43
26.85
29.68
SOFA score before PE
73
3.00
8.00
5.10
1.12
4.00
5.00
6.00
Mean decrease rate of total bilirubin
73
−65.51
56.84
10.89
18.11
0.80
12.63
22.04
Mean increase rate of prothrombin activity
73
−48.94
89.36
11.36
19.49
1.75
9.03
18.97
Mean decrease rate of MELD score
73
−48.69
30.37
3.49
13.01
−1.88
5.34
12.52
Decrease rate of total bilirubin after the first PE
73
−65.51
56.84
11.45
21.31
−2.46
14.51
24.59
Increase rate of prothrombin activity after the first PE
73
−48.94
138.10
22.45
32.30
2.19
21.88
40.66
Decrease rate of MELD score after the first PE
73
−48.69
41.35
7.79
15.64
0.73
11.05
19.33
Hospital day
73
3
90
25.95
15.86
15.50
23.00
33.00
ALF, acute liver failure; PE, plasma exchange; BMI, body mass index; MELD score, model for end-stage liver disease; SOFA score, sequential organ failure assessment score.
