Combined Age with Mean Decrease Rates of Total Bilirubin and MELD Score as a Novel and Simple Clinical Predictor on 90-Day Transplant-Free Mortality in Adult Patients with Acute Liver Failure Undergoing Plasma Exchange: A Single-Center Retrospective Study
Table 2
Univariate analysis of 90-day transplant-free mortality in adult patients with ALF undergoing PE.
Variable
Death group (N = 23)
Survival group (N = 50)
X2/t/Z
Gender (male/female)
20/3
36/14
1.973
0.160
Age
55.43 ± 13.91
45.70 ± 11.19
−3.194
0.002
Height
1.71 ± 0.07
1.70 ± 0.09
−0.764
0.447
Weight
72.26 ± 11.46
69.94 ± 11.11
−0.821
0.414
BMI
24.54 ± 2.62
24.36 ± 3.53
−0.215
0.830
Total bilirubin before PE
464.53 ± 145.97
440.91 ± 150.51
−0.628
0.532
Direct bilirubin before PE
383.00 ± 137.92
350.06 ± 130.73
−0.983
0.329
Indirect bilirubin before PE
81.52 ± 54.08
91.40 ± 51.42
0.750
0.456
Prothrombin activity before PE
31.58 ± 13.19
29.46 ± 11.49
−0.618
0.537
MELD score before PE
26.55 ± 5.77
26.72 ± 6.07
0.114
0.909
SOFA score before PE
5.43 ± 1.24
4.94 ± 1.04
−1.622
0.105
Mean decrease rate of total bilirubin
−1.22 ± 20.08
16.46 ± 14.17
−3.752
≤0.001
Mean increase rate of prothrombin activity
2.91 ± 27.35
15.25 ± 13.18
2.057
0.048
Mean decrease rate of MELD score
−7.60 ± 14.94
8.59 ± 8.03
4.881
≤0.001
Decrease rate of total bilirubin after the first PE
0.64 ± 24.60
16.42 ± 17.77
3.112
0.003
Increase rate of prothrombin activity after the first PE
7.09 ± 39.10
29.52 ± 26.16
2.505
0.018
Decrease rate of MELD score after the first PE
−0.05 ± 20.68
11.40 ± 11.20
2.494
0.019
ALF, acute liver failure; PE, plasma exchange; BMI, body mass index; MELD score, model for end-stage liver disease; SOFA score, sequential organ failure assessment score.
