Research Article

miR-325-3p Reduces Proliferation and Promotes Apoptosis of Gastric Cancer Cells by Inhibiting Human Antigen R

Figure 1

Knockdown of HuR inhibited proliferation and promoted apoptosis in SGC-7901 and HGC-27 cells. (a, d) Detecting the apoptosis cells of SGC-7901 and HGC-27 by TUNEL assay after HuR knockdown. (b, e) Evaluating the proliferation by CCK-8 assay after HuR knockdown within 96 hours. (c, f) Protein levels of BAX, Caspase 3 and HuR by Western blot. (g, h) Apoptosis-related gene expression levels by qRT-PCR after HuR knockdown (, , , and , compared to siNC group).
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