A Meta-Analysis of MiRNA-497 and Prognosis of Hepatocellular Carcinoma

Table 1

The main characteristics of the studies included in this meta-analysis.

Author	Year	Method	Number	miR-497 expression				Cut-off	Vascular infiltration		Follow-up	Outcome	NOS
				Low		High			Low	High	(months)
				TNM I∼II	III∼IV	I∼II	III∼IV
Zhang et al.	2016	qRT-PCR	86	28	15	39	4	Median	24	16	60	OS	7
Xie et al.	2017	qRT-PCR	61	35	5	11	10	Median	21	2	60	OS	7
Zhang et al.	2018	qRT-PCR	125	30	34	41	22	Median	41	25	60	OS	7
Zhao et al.	2019	qRT-PCR	75	—	—	—	—	Median	26	18	30	OS	6
Ali et al.	2021	qRT-PCR	60	—	—	—	—	Median	—	—	—	OS	6
Chen et al.	2021	qRT-PCR	50	9	16	17	8	Median	16	10	60	OS	8

Note. The dashes mean no data. qRT-PCR: quantitative real-time PCR; TNM: Tumor-node-metastasis; OS: overall survival; NOS: Newcastle-Ottawa​ scale.