Research Article

Clinical Outcomes of Ileostomy Closure during versus after Adjuvant Chemotherapy in Patients with Rectal Cancer

Table 2

Data related to ileostomy closure.

Group AGroup B value
(n = 115), (%)(n = 100), (%)

Interval to ileostomy closure (day; IQR)98 (83–110)179 (152–211)<0.001
Operation time (min)87.41 ± 34.2991.21 ± 37.990.442
Blooding loss (mL)23.77 ± 16.7225.15 ± 17.890.558
Time to first flatus (day)3.28 ± 1.083.22 ± 0.920.673
Time to fully oral nutrition (day)3.30 ± 1.083.32 ± 1.130.872
Hospital stay (day)5.17 ± 1.875.31 ± 1.680.558
Postoperative complications18/115 (15.7%)22/100 (22.0%)0.102
Clavien–Dindo classification
 Grade I8 (7.0%)8 (8.0%)
 Grade II2 (1.7%)10 (10.0%)
 Grade IIIa2 (1.7%)1 (1.0%)
 Grade IIIb6 (5.2%)3 (3.0%)
Chemotherapy regimens0.686
 Monotherapy2217
 Combined chemotherapy9383
Postoperative infection2 (1.7%)4 (4.0%)0.315
Cost (yuan)39613.28 ± 11004.3937142.76 ± 12427.550.124
Increased creatinine (μmol/L)8.43 ± 31.264.95 ± 14.730.309
Decreased BMI (kg/m2)0.91 ± 1.710.67 ± 1.460.275
Anastomotic evaluation method
 Endoscope99 (86.1%)91 (91.0%)0.262
 Endoscope + CT74 (64.3%)69 (69.0%)0.471
Rectal anastomosis stenosis14 (12.2%)23 (23.0%)0.036
Disused colitis29 (25.2%)25 (25%)0.971
Chemotherapy cycles (times)5.19 ± 1.535.72 ± 1.410.009
Follow-up time (IQR)36 (28–47)36 (29–51)0.393
Postoperative regular follow-up78 (67.8%)66 (66.0%)0.726

IQR, interquartile range; BMI, body mass index; CT, computed tomography; .