Research Article

Hepatitis C Attributable Healthcare Costs and Mortality among Immigrants: A Population-Based Matched Cohort Study

Table 1

Characteristics of the study cohort.

PrematchedMatchedUnmatched
Exposed N = 6,914Unexposed N = 120,693SMDExposed N = 5,575Unexposed N = 5,575SMDExposed N = 1,339

Index year, mean (sd)2009 (4.0)2013 (4.0)0.742010 (4.0)2010 (4.0)0.002009 (4.5)
Age at diagnosis, years, mean (sd)48.1 (16.1)39.1 (17.7)0.5046.6 (14.8)46.6 (14.8)0.0054.2 (19.6)
Birth year, n (%)
 <19451,141 (16.5)7,799 (6.5)0.32663 (11.9)663 (11.9)0.00478 (35.7)
 1945–19652,895 (41.9)29,993 (24.9)0.372,474 (44.4)2,474 (44.4)0.00421 (31.4)
 >19652,878 (41.6)82,901 (68.7)0.572,438 (43.7)2,438 (43.7)0.00440 (32.9)
Male sex, n (%)3,648 (52.8)58,413 (48.4)0.092,891 (51.9)2,891 (51.9)0.00757 (56.5)
Landing year, mean (sd)2001 (8.0)2003 (8.0)0.262002 (8.0)1999 (8.0)0.381997 (7.5)
Years of education, mean (sd)10.5 (5.5)10.3 (6.3)0.0310.98 (5.3)11.1 (5.1)0.038.3 (5.9)
Rural, n (%)64 (0.9)1,333 (1.1)0.0254 (1.0)46 (0.8)0.0210 (0.7)
Neighborhood income quintile, n (%)
 1st quintile (lowest)2,490 (36.0)36,752 (30.5)0.121,909 (34.2)1,946 (34.9)0.01581 (43.4)
 2nd quintile1,507 (21.8)27,210 (22.5)0.021,252 (22.5)1,271 (22.8)0.01255 (19.0)
 3rd quintile1,286 (18.6)23,042 (19.1)0.011,071 (19.2)1,074 (19.3)0.00215 (16.1)
 4th quintile1,054 (15.2)19,581 (16.2)0.03880 (15.8)797 (14.3)0.04174 (13.0)
 5th quintile577 (8.3)14,108 (11.7)0.11463 (8.3)487 (8.7)0.02114 (8.5)
Residential instability quintile, n (%)
 1st quintile (lowest)1,817 (26.3)32,216 (26.7)0.011,528 (27.4)1,522 (27.3)0.00289 (21.6)
 2nd quintile893 (12.9)17,254 (14.3)0.00724 (13.0)752 (13.5)0.01169 (12.6)
 3rd quintile790 (11.4)14,934 (12.4)0.03659 (11.8)645 (11.6)0.01131 (9.8)
 4th quintile1,128 (16.3)19,091 (15.8)0.01882 (15.8)956 (17.1)0.04246 (18.4)
 5th quintile2,286 (33.1)37,198 (30.8)0.051,782 (32.0)1,700 (30.5)0.03504 (37.6)
Material deprivation quintile, n (%)
 1st quintile (lowest)767 (11.1)17,130 (14.2)0.09624 (11.2)661 (11.9)0.02143 (10.7)
 2nd quintile888 (12.8)18,514 (15.3)0.07745 (13.4)685 (12.3)0.03143 (10.7)
 3rd quintile1,202 (17.4)21,319 (17.7)0.01982 (17.6)988 (17.7)0.00220 (16.4)
 4th quintile1,548 (22.4)27,284 (22.6)0.011,296 (23.2)1,232 (22.1)0.03252 (18.8)
 5th quintile2,509 (36.3)36,386 (30.1)0.131,928 (34.6)2,009 (36.0)0.03581 (43.4)
Ethnic concentration quintile, n (%)
 1st quintile (lowest)145 (2.1)2,759 (2.3)0.01103 (1.8)113 (2.0)0.0142 (3.1)
 2nd quintile248 (3.6)4,522 (3.7)0.01192 (3.4)152 (2.7)0.0456 (4.2)
 3rd quintile491 (7.1)9,443 (7.8)0.03372 (6.7)371 (6.7)0.00119 (8.9)
 4th quintile1,366 (19.8)24,479 (20.3)0.011,082 (19.4)981 (17.6)0.05284 (21.2)
 5th quintile4,664 (67.5)79,490 (65.9)0.033,826 (68.6)3,958 (71.0)0.05838 (62.6)
Dependency quintile, n (%)
 1st quintile (lowest)2,660 (38.5)46,363 (38.4)0.002,202 (39.5)2,080 (37.3)0.05458 (34.2)
 2nd quintile1,695 (24.5)28,288 (23.4)0.031,384 (24.8)1,322 (23.9)0.02311 (23.2)
 3rd quintile1,106 (16.0)19,313 (16.0)0.00862 (15.5)950 (17.0)0.04244 (18.2)
 4th quintile800 (11.6)15,054 (12.5)0.03642 (11.5)701 (12.6)0.03158 (11.8)
 5th quintile653 (9.4)11,675 (9.7)0.01485 (8.7)512 (9.2)0.02168 (12.5)
Substance use disorder, n (%)496 (7.2)1,321 (1.1)0.3159 (1.1)59 (1.1)0.00437 (32.6)
HIV positivity, n (%)27 (0.4)21 (0.02)0.0820 (0.4)<6 (<0.1)0.077 (0.5)
ADG categories, n (%)
 0–33,489 (30.5)84,704 (70.2)0.413,267 (58.6)3,267 (58.6)0.00222 (16.6)
 4–72,445 (35.4)29,971 (24.8)0.231,984 (35.6)1,984 (35.6)0.00461 (34.4)
 8–10668 (9.7)4,946 (4.1)0.22289 (5.2)289 (5.2)0.00379 (28.3)
 >11312 (4.5)1,072 (0.9)0.2335 (0.6)35 (0.6)0.00277 (20.7)

The index year is the year of CHC diagnosis. ADG: aggregated diagnostic groups; CHC: chronic hepatitis C; HIV: human immunodeficiency virus; N: number of observations; sd: standard deviation; SMD: standardized difference in means.