Evaluation of Risk Factors for Antibiotic Resistance in Patients with Nosocomial Infections Caused by Pseudomonas aeruginosa

Table 1

Demographic and clinical characteristics of patients with P. aeruginosa related nosocomial infection.

Characteristics	Number of patients (%); (: 120)
Age; years (mean ± SD)	58.4 ± 19.2
>60 years old	70–58.3
Male/female	62–50.8/58–49.2
Intensive care unit (ICU)
NR-ICU	34–28.3
AR-ICU	56–46.6
NRS-ICU	34–28.3
Stay at ICU (mean ± SD)	112.7 ± 87.8
Intensive care unit stay > 60 days	82–68.3
Polymicrobial infection	90–75
Multiple isolation of P. aeruginosa	50–41.7
Time at risk (mean ± SD)	55.4 ± 52.4
APACHE II score (mean ± SD) (at time of isolation)	23.6 ± 4.14
Invasive procedures and comorbid disease
Mechanic ventilation	96–80
Enteral nutrition	105–87.5
Total parenteral nutrition	87–72.5
Thoracotomy tube	17–14.2
Urinary catheterization	119–99.2
Central venous catheterization	108–90
History of cerebrovascular disease	78–65
History of cardiovascular disease	98–81.7
History of surgical operation	40–33.3
History of chronic renal disease	32–26.7
History of malignancy	69–57.5
Prior antibiotic use
Carbapenems	73–60.8
Meropenem	67–90.1
Piperacillin-tazobactam	50–41.7
Amikacin	44–36.7
Teicoplanin	38–31.7
Cefazolin	29–24.2
Ceftriaxone	22–18.3
Ciprofloxacin	10–8.3
Ceftazidime	9–7.5

NR-ICU: neurology intensive care unit, AR-ICU: anesthesia-reanimation intensive care unit, and NRS-ICU: neurosurgery intensive care unit.