Clinical Utility of Rapid Pathogen Identification for Detecting the Causative Organisms in Sepsis: A Single-Center Study in Korea
Table 1
Baseline characteristics of the preintervention and postintervention groups.
Variable
Preintervention group ()
Postintervention group ()
Age (years)
63.2 ± 14.0
66.4 ± 13.6
0.26
Male (sex)
25 (63)
30 (52)
0.29
Comorbidity
Diabetes
8 (20)
21 (36)
0.08
Chronic heart failure
3 (8)
10 (17)
0.16
Cerebrovascular accident
2 (5)
7 (12)
0.30
Chronic pulmonary disease
2 (5)
6 (10)
0.47
Liver cirrhosis
3 (8)
6 (10)
0.73
Chronic kidney disease
3 (8)
2 (3)
0.40
Malignancy
18 (45)
9 (16)
0.001
No. of SIRS criteria met at ICU admission
3.3 ± 0.7
3.4 ± 0.7
0.59
qSOFA score at ICU admission
2.3 ± 0.5
2.3 ± 0.5
0.98
Altered mentation
28 (70)
44 (76)
0.52
Respiratory rate ≥22 breaths/min
32 (80)
49 (85)
0.57
Systolic blood pressure ≤100 mmHg
33 (83)
42 (72)
0.25
Within 72 h of ICU admission
Mechanical ventilation
24 (60)
31 (53)
0.52
Neuromuscular blockers
6 (15)
14 (24)
0.27
Vasopressor use
28 (70)
40 (69)
0.91
Renal replacement therapy
20 (50)
18 (31)
0.06
Source of bacteremia
Respiratory
17 (43)
25 (43)
0.95
Intra-abdominal
11 (28)
15 (26)
0.86
Genitourinary
4 (10)
5 (9)
>0.99
Skin and soft tissue/bone and joint
3 (8)
10 (17)
0.16
Vascular catheter
2 (5)
4 (7)
>0.99
The data are presented as mean ± standard deviation or number (percentage) of patients. values indicate the results of comparing the preintervention and postintervention groups by using Student’s t-, chi-squared, or Fisher’s exact tests. SIRS: systemic inflammatory response syndrome; qSOFA: quick Sequential Organ Failure Assessment; ICU: intensive care unit.