Risk Factors Associated with Dengue Transmission and Spatial Distribution of High Seroprevalence in Schoolchildren from the Urban Area of Medellin, Colombia

Table 4

Characterization of antibody response to dengue virus serotypes using the ELISPOT-MNT₅₀ in the studied schoolchildren population in 2010–2012 from Medellin.

	2010	2011	2012	Overall
		% (n)	% (n)	% (n)	% (n)
Negative	2.8 (5)	7.9 (7)	7.7 (1)	4.7 (13)
Monotypic	26.7 (47)	19.1 (17)	0.0 (0)	23.0 (64)
DENV1	4.0 (7)	5.6 (5)	—	4.3 (12)
DENV2	6.2 (11)	5.6 (5)	—	5.6 (16)
DENV3	1.1 (2)	0.0 (0)	—	0.7 (2)
DENV4	15.3 (27)	7.9 (7)	—	12.2 (34)
Multitypic	70.4 (124)	73.0 (65)	92.3 (12)	72.3 (201)
DENV1/2	0.0 (0)	3.4 (3)	0.0 (0)	1.1 (3)
DENV1/3	1.1 (2)	0.0 (0)	0.0 (0)	0.7 (2)
DENV1/4	5.1 (9)	6.7 (6)	15.4 (2)	6.1 (17)
DENV2/3	1.7 (3)	0.0 (0)	0.0 (0)	1.1 (3)
DENV2/4	17.0 (30)	5.6 (5)	7.7 (1)	12.9 (36)
DENV3/4	2.8 (5)	0.0 (0)	0.0 (0)	1.8 (5)
DENV1/3/4	4.5 (8)	1.1 (1)	23.1 (3)	4.3 (12)
DENV2/3/4	2.3 (4)	0.0 (0)	0.0 (0)	1.4 (4)
DENV1/2/4	19.9 (35)	22.5(20)	7.7 (1)	20.1 (56)
DENV1/2/3/4	15.9 (28)	33.7 (30)	38.5 (5)	22.7 (63)