Research Article
The Abundance of Plasmid-Mediated Quinolone Resistance Genes in Enterobacter cloacae Strains Isolated from Clinical Specimens in Kermanshah, Iran
Table 3
Association between antibiotic resistance in ESBL-positive and ESBL-negative E. cloacae isolates.
| | Antibiotic | Total resistance no (%) | ESBL-positive 65 isolates | ESBL-negative 48 isolates | -value | | R | I | S | R | I | S | R | I | S |
| | NA | 68 (60.2) | 4 (3.5) | 41 (36.3) | 49 (75.4) | 2 (3.1) | 14 (21.5) | 19 (39.6) | 2 (4.2) | 27 (56.2) | 0.001 | | CIP | 66 (58.4) | 8 (7.1) | 39 (34.5) | 47 (72.3) | 5 (7.7) | 13 (20) | 19 (39.6) | 3 (6.2) | 26 (54.2) | 0.001 | | NOR | 56 (49.6) | 8 (7.1) | 49 (43.4) | 39 (60) | 4 (6.2) | 22 (33.8) | 17 (35.4) | 4 (8.4) | 27 (56.2) | 0.83 | | LEV | 45 (39.8) | 3 (2.7) | 65 (57.5) | 36 (55.4) | 0 | 29 (44.6) | 8 (16.6) | 4 (8.4) | 36 (75) | 0.75 | | GAT | 38 (33.6) | 0 | 75 (66.4) | 30 (46.2) | 0 | 35 (53.8) | 8 (16.6) | 0 | 40 (83.4) | 0.001 | | OFX | 49 (43.4) | 4 (3.5) | 60 (53.1) | 35 (53.8) | 3 (4.6) | 27 (41.6) | 13 (27.1) | 2 (4.2) | 33 (68.7) | 0.013 | | CTX | 57 (50.4) | 0 | 56 (49.6) | 51 (78.5) | 0 | 14 (21.5) | 6 (12.5) | 0 | 42 (87.5) | 0.001 | | CAZ | 51 (45.1) | 0 | 62 (54.9) | 51 (78.5) | 2 (3.1) | 12 (18.4) | 2 (4.2) | 0 | 46 (95.8) | 0.001 | | CRO | 63 (55.8) | 0 | 50 (44.2) | 55 (84.6) | 0 | 10 (15.4) | 8 (16.6) | 0 | 40 (83.4) | 0.32 | | ATM | 53 (46.9) | 2 (1.8) | 58 (51.3) | 50 (76.9) | 0 | 15 (23.1) | 1 (2.1) | 0 | 47 (97.9) | 0.001 | | GM | 57 (50.4) | 2 (1.8) | 54 (47.8) | 52 (80) | 1 (1.6) | 12 (18.4) | 5 (10.4) | 1 (2.1) | 42 (87.5) | 0.001 | | AK | 44 (38.9) | 2 (1.8) | 67 (59.3) | 41 (63.1) | 1 (1.6) | 23 (35.3) | 3 (6.2) | 1 (2.1) | 44 (91.7) | 0.001 | | TN | 66 (58.4) | 3 (2.7) | 44 (38.9) | 38 (58.5) | 3 (4.6) | 24 (36.9) | 28 (58.3) | 0 | 20 (41.7) | 0.358 | | IMI | 16 (14.2) | 6 (5.3) | 91 (80.5) | 10 (15.4) | 3 (4.6) | 52 (80) | 6 (12.5) | 3 (6.2) | 39 (81.3) | 0.270 | | NI | 34 (30.1) | 0 | 79 (69.9) | 23 (35.4) | 0 | 42 (64.6) | 11 (22.9) | 0 | 37 (77.1) | 0.155 | | CO | 11 (9.7) | 2 (1.8) | 100 (88.5) | 9 (13.8) | 0 | 56 (86.2) | 2 (4.2) | 2 (4.2) | 44 (91.6) | 0.156 | | C | 38 (33.6) | 0 | 75 (66.4) | 24 (36.9) | 0 | 41 (63.1) | 14 (29.2) | 0 | 34 (70.8) | 0.290 |
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R: resistance; S: sensitive; I: intermediate. NA: nalidixic acid; CIP: ciprofloxacin; NOR: norfloxacin; LEV: levofloxacin; GAT: gatifloxacin; OFX: ofloxacin; CTX: cefotaxime; CAZ: ceftazidime; CRO: ceftriaxone; ATM: aztreonam; GM: gentamicin; AK: amikacin; TN: tobramycin; IMI: imipenem; NI: nitrofurantoin; CO: colistin; C: chloramphenicol.
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