Research Article

Seroprevalence of IgM/IgG and Neutralizing Antibodies against SARS-CoV-2 in Unvaccinated Young Adults from Mexico Who Reported Not Having Had a Previous COVID-19 Infection

Table 2

Rapid test and NAbs for SARS-CoV-2.

TestTotal unvaccinated young adults n = 171Prior COVID-19 by self-report value
Yes
21.05% (n = 36)
No
78.94% (n = 135)

Rapid antibody test
 Negative42.6% (73/171)13.9% (5/36)50.4% (68/135)<0.0001
 Positive57.3% (98/171)86.1% (31/36)49.6% (67/135)
  IgM3.1% (3/98)0% (0/31)4.5% (3/67)0.488
  IgM + IgG9.2% (9/98)9.7% (3/31)8.9% (6/67)
  IgG87.8% (86/98)90.3% (28/31)86.6% (58/67)
Neutralizing antibodies
 Negative (<30%)42.7% (73/171)8.3% (3/36)51.9% (70/135)<0.0001
 Positive (>30%)57.3% (98/171)91.7% (33/36)48.1% (65/135)
 % neutralization48.36 (9.415–96.01)94.3 (68.14–96.96)26.07 (6.035–93.130)<0.0001

-values were calculated by Fisher’s exact, the Mann–Whitney U (%(n)) or chi-square test for the groups (median (IQR)).