Preliminary ¹⁹F-MRS Study of Tumor Cell Proliferation with 3′-deoxy-3′-fluorothymidine and Its Metabolite (FLT-MP)

Figure 3

¹⁹F NMR spectra of MCF-7 cell suspensions treated with FLT (0.1 mg/1 × 10⁷ cells) as a function of time (d–g). The quantification in a relative ratio of FLT to FLT-MP was indicated. Typical spectra of (a) FLT (−175.4 ppm), (b) FLT-MP (−174.4 ppm), and (c) MCF-7 cells without FLT addition.