Use of Cyclic Backbone NGR-Based SPECT to Increase Efficacy of Postmyocardial Infarction Angiogenesis Imaging

Table 1

Analytical mass data of coNGR-based tracer constructs. Masses are given in Da. From top to bottom, mass of linear peptide (thioester), cyclic peptide after NCL, and the lysine wedge with four SMCC linkers are represented. Last two rows represent mass of DTPA-coNGR and DTPA-co(NGR)₄, respectively.

Compound	Monoisotopic mass	Molecular weight	Measured
CNGRG-MpaL	705.31	705.81	705.32
coNGR	487.20	487.54	487.22
Lys(Thz)-(Lys)2-(SMCC)4	1520.77	1521.84	1520.83
DTPA-coNGR	1170.50	1171.25	1170.49
DTPA-co(NGR)4	4140.86	4143.69	4140.76