Use of Ultrasmall Superparamagnetic Iron Oxide Enhanced Susceptibility Weighted Imaging and Mean Vessel Density Imaging to Monitor Antiangiogenic Effects of Sorafenib on Experimental Hepatocellular Carcinoma

<div>Serial measurements of intratumoral susceptibility signal intensity (ITSS) (white arrows) in the treated and control tumors on USPIO-enhanced SWI. In the treated tumors, ITSS is scored as grade 1 at 7 days (a), grade 2 at 14 days (b), and grade 2 at 21 days (c). In the control tumors, ITSS is scored as grade 3 at 7 days (d), grade 3 at 14 days (e), and grade 4 at 21 days (f). Smaller size is noted in the treated tumors than the control at each time point.</div>

Contrast Media & Molecular Imaging

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Figure 2: Use of Ultrasmall Superparamagnetic Iron Oxide Enhanced Susceptibility Weighted Imaging and Mean Vessel Density Imaging to Monitor Antiangiogenic Effects of Sorafenib on Experimental Hepatocellular Carcinoma 

Figure 2 | Use of Ultrasmall Superparamagnetic Iron Oxide Enhanced Susceptibility Weighted Imaging and Mean Vessel Density Imaging to Monitor Antiangiogenic Effects of Sorafenib on Experimental Hepatocellular Carcinoma 