A Hyperfluorinated Hydrophilic Molecule for Aqueous ¹⁹F MRI Contrast Media

Figure 2

Preliminary toxicity evaluation of ET1084. (a) Probit analysis to determine LC50 values of ET1084 against RAW264.7 and ImKCs; (b) LC50 values, slope, the corresponding 95% confidence limit (CL), and goodness of fit (R²); (c) cell viability of both cell lines treated with 20 mM ET1084 compared to untreated cells and 0.1 mM BMH-21 (positive control); (d) IFs plots following treatment of E. coli with different concentrations of ET1084 and 4-NQO (positive control). IFs < 1.5 indicate no genotoxicity.

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