Research Article
Presaturation Power Adjusted Pulsed CEST: A Method to Increase Independence of Target CEST Signals
Figure 2
(a) The z-spectra exhibit a reduction in bulk water signal as a result of chemical exchange of water protons with each substance (nicotinamide at 3.5 ppm, glutamate at 3.0 ppm, creatine at 2.0 ppm, and glucose at 1.0 ppm, resp.). The results are showed in the magnetization transfer asymmetry ratio (MTRasym) analysis (b) and the fitting (Lorentzian) analysis (c). The orange line mimic the summed up MTRasym curves of all four substances (virtual 4-high) (b). The MTRasym in the virtual 4-high was similar to that in the real 4-high (virtual (orange) versus real (black)) (d).
| (a) |
| (b) |
| (c) |
| (d) |