Combined Volumetric and Density Analyses of Contrast-Enhanced CT Imaging to Assess Drug Therapy Response in Gastroenteropancreatic Neuroendocrine Diffuse Liver Metastasis

Table 2

CT evaluation of treatment response of the 25 patients with GEP-NETs.

Case no.	Changes (%)				RECIST 1.1 response	PFS (months)
	Density	Volume	Size	Density and volume
1	1.68	287.33	43.75	289.01	PD	2.0
2	22.86	229.06	−11.55	251.92	SD	3.4
3	17.05	31.79	22.91	48.84	PD	—
4	14.89	25.28	−6.3	40.17	SD	4.3
5	17.77	−28.74	−39.28	−10.97	PR	6.2
6	−2.95	−88.68	−76.76	−91.63	PR	9.4
7	−31.67	296	193.75	264.33	PD	3.3
8	11	81.25	47.62	92.25	PD	3.0
9	10.99	5	−22.96	15.99	PR	5.7
10	0.97	9.89	−5.22	10.86	SD	4.8
11	−27.84	−74.55	−10.94	−102.39	SD	9.8
12	−4.7	131.25	97.06	126.55	PD	1.9
13	−16.48	57.86	16.9	41.38	SD	—
14	−13.13	43.48	−14.47	30.35	SD	5.7
15	12.87	152.91	17.7	165.78	SD	3.2
16	5.39	−27.53	−58.96	−22.14	PR	—
17	0.65	33.61	−10.68	34.26	SD	—
18	5.79	199.12	−5.73	204.91	SD	5.6
19	−30.16	−1.61	77.1	−31.77	PD	4.4
20	28	18.24	11.28	46.24	SD	2.4
21	1.46	13.73	−2.38	15.19	SD	4.9
22	−24.17	112.5	42.86	88.33	PD	1.8
23	1.69	34.67	2.13	36.36	SD	4.2
24	23.67	5.24	−6.69	28.91	SD	3.5
25	29.23	49.52	−18.43	78.75	SD	3.5