Functionalization of Gadolinium Chelates Silica Nanoparticle through Silane Chemistry for Simultaneous MRI/⁶⁴Cu PET Imaging

Figure 1

(a) The reaction scheme of the synthesis of APTES-DOTAGA (upper) and APTES-NODAGA (lower); (b) the reaction scheme of the functionalization of APTES-DOTAGA and APTES-NODAG on SiGdNP.

(a)

(b)