Research Article

Detecting GPC3-Expressing Hepatocellular Carcinoma with L5 Peptide-Guided Pretargeting Approach: In Vitro and In Vivo MR Imaging Experiments

Figure 7

In vivo MR imaging of GPC3-expressing tumors via L5 peptide-guided two-step pretargeting approach. The tumor cells were implanted subcutaneously in the back of animals. On 1 hour postinjection T2WI image, xenografts (arrowheads) showed significant signal decrease in the pretargeting group (PT) but not in the nonpretargeting (NT) or control group.