Prospective of ⁶⁸Ga Radionuclide Contribution to the Development of Imaging Agents for Infection and Inflammation

Figure 1

PET images of the distribution of [⁶⁸Ga]Ga-DOTAVAP-P1, [⁶⁸Ga]Ga-DOTAVAP-PEG-P1, and [⁶⁸Ga]Ga-DOTA-Siglec-9 in turpentine-induced rat model of sterile inflammation. All three peptide analogues showed target-to-nontarget ratio above 6 with rapid accumulation in the inflammation site and renal clearance. Adapted from [57].