Research Article
Prognostic Value of Functional Parameters of 18F-FDG-PET Images in Patients with Primary Renal/Adrenal Lymphoma
Table 3
Univariate and multivariate Cox regression analyses of factors associated with OS.
| Variables | Median OS (month) | Univariate analysis | Multivariate analysis | HR (95% CI) | | HR (95% CI) | |
| Age (year) | <50 | 20.63 | | 0.745 | | | ≥50 | 17.55 | | | | Gender | Male | 17.00 | | 0.347 | | | Female | 22.00 | | | | Location | Kidney | 14.00 | | 0.432 | | | Adrenal gland | 17.50 | | | | | Kidney + adrenal gland | 20.00 | | | | | Ann Arbor stage | I∼III | 27.44 | 11.150 (1.220–101.924) | 0.033 | | | IV | 11.10 | | | | | Subtype/origin | B cell | 21.62 | | 0.244 | | | T cell | 2.00 | | | | | NK cell | 15.00 | | | | |
| 18F-FDG-PET parameters | SUVmax | <7.37 | 25.20 | | 0.264 | | | ≥7.37 | 16.57 | | | | SUVmean | <7.00 | 23.25 | | 0.575 | | | ≥7.00 | 15.64 | | | | | MTV | <88.80 | 21.13 | 5.044 (0.983–25.882) | 0.052 | | | ≥88.80 | 10.25 | | | | | TLG | <13.05 | 31.00 | | 0.065 | | | ≥13.05 | 15.60 | | | | |
| Texture features | GLCM_Correlation | <0.695 | 22.38 | 5.089 (0.911–28.421) | 0.064 | | | ≥0.695 | 11.17 | | | | | GLRLM_HGRE | <171.95 | 28.13 | | 0.076 | | | ≥171.95 | 12.09 | | | | | GLRLM_SRHGE | <163.2 | 28.13 | | 0.076 | | | ≥163.2 | 12.09 | | | | | GLRLM_LRHGE | <215.8 | 28.13 | | 0.076 | | | ≥215.8 | 12.09 | | | | | GLRLM_RLNU | <216.6 | 25.00 | 9.016 (1.041–78.112) | 0.046 | 9.016 (1.041–78.112) | 0.046 | ≥216.6 | 10.38 | | | | | GLZLM_HGZE | <205.05 | 28.13 | | 0.076 | | | ≥205.05 | 12.09 | | | | | GLZLM_GLNU | <2.9 | 30.43 | 9.366 (1.096–80.051) | 0.041 | | | ≥2.9 | 12.08 | | | | | GLZLM_ZLNU | <9.75 | 28.13 | | 0.076 | | | ≥9.75 | 12.09 | | | | | HISTO_Entropy | <12.6 | 28.13 | | 0.076 | | | ≥12.6 | 12.09 | | | | | GLCM_Entropy | <71.14 | 27.22 | 5.639 (1.051–30.244) | 0.044 | | | ≥71.14 | 11.30 | | | | |
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∗p < 0.05.
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