Neutrophil Elastase Activity Imaging: Recent Approaches in the Design and Applications of Activity-Based Probes and Substrate-Based Probes

<div>Overall principle of activity-based probe (ABP). Warhead (grey triangle) structurally matches with the target protease (purple). Active ABP can be detected by the tag (blue star). AA<sub>1</sub>-AA<sub><i>n</i></sub> indicates amino acid position in the specific peptide.</div>

Contrast Media & Molecular Imaging

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Figure 2

Figure 2: Neutrophil Elastase Activity Imaging: Recent Approaches in the Design and Applications of Activity-Based Probes and Substrate-Based Probes 