Research Article

Paired-Agent Fluorescence Molecular Imaging of Sentinel Lymph Nodes Using Indocyanine Green as a Control Agent for Antibody-Based Targeted Agents

Figure 5

Fluorescence intensity of ICG in albumin as a function of ICG concentration. Fluorescence maximum was observed at 50 μM (quenching threshold) with the concentration range 0.001–1000 μM in albumin concentration equivalent to concentration in the lymphatic system (a). A correlation between ICG concentration and its fluorescence intensity is presented in (b). The dashed line represents the linear regression of the data.
(a)
(b)