Table 1: Variables used in the hybrid model: The variable of the dimensional system ((1a), (1b), (1c)) and ((2a), (2b), (2c), (2d)), a description, their units, the computation for the corresponding nondimensional parameters and references.

Variable Description Unit Formula of Reference

Cancer cell Cells [16, 23]
Nutrient concentration M O2 c [16, 23]
ECM [16, 23]
MDE [16, 19, 23]