Molecular Dynamics Simulation of HIV Fusion Inhibitor T-1249: Insights on Peptide-Lipid Interaction

Figure 1

(a) T-1249 aminoacid sequence. (b) POPC structure and atom numbering. (c) Cholesterol structure and atom numbering. (d) T-1249/POPC final structure snapshot. (e) T-1249/POPC/Chol final structure snapshot. Reprinted with permission from [15]. Copyright 2010 Elsevier.